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Lasercut 5.3


developing tumors. Injection of anti-CD4 antibody into tumor-bearing mice will eliminate the majority of tumor-infiltrating lymphocytes, thereby



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Lasercut 5.3


LaserCutter & Desktop LaserCutter & Desktop LaserCut Desktop See also CNC technology G-code Laser cutting Machine controller List of G-code editors References Category:G-codeExpression of moesin and moesin-interacting proteins in epithelial cells: influence of genotoxic stress. E-cadherin (E-cad) is the prototype cell-cell adhesion protein in epithelial tissues. Moesin, an actin-associated actin-bundling protein, binds to the cytoplasmic domain of E-cad, but the extent to which moesin functions as an E-cad-binding protein in non-epithelial cells is unknown. In this study, we show that moesin and several moesin-interacting proteins are expressed in the cell lines used to establish cell lines, including several non-epithelial cell lines and an immortalized, but non-tumorigenic, human mammary epithelial cell line (HME). Moesin expression in non-epithelial cell lines was shown to be responsive to genotoxic stress and to be significantly decreased by overexpression of wild-type p53, but not by overexpression of mutant p53. Moesin expression in the cell lines showed reciprocal patterns of expression relative to E-cad, consistent with a positive correlation between E-cad and moesin expression. The moesin-interacting proteins, FAT and FRG, were also expressed in all cell lines and showed varying patterns of expression relative to moesin. FRG was responsive to genotoxic stress, whereas FAT was expressed in a constitutive manner. Based on our observations and the finding that FRG is essential for moesin-mediated E-cad adhesion, we speculate that moesin functions as an E-cad-binding protein in some non-epithelial cell lines, including breast carcinoma cell lines.When the Montreal Canadiens dropped the first two games of the Stanley Cup Final, it was bad news for the local fans, who turned out to be a decent percentage of the arena. On Saturday night, when they came back to win, it was still bad news for the local fans. The local fans, that is, who stayed home to watch the game on a huge, high-definition TV and own









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